SSRI s may boost the painkilling effects of some tricyclic antidepressants by increasing the levels of tricyclic antidepressants in your blood. WebMD Antidepressants can directly affect how your brain senses certain kinds of pain. The Use of Antidepressants for Managing Chronic Pain Or can antidepressants help with pain even for people without any symptoms of depression? Also, if you have depression or anxiety, those meds can ease those symptoms, which can also help ease your pain.
SSRI s, which include drugs such as paroxetine (Paxil) and fluoxetine (Sarafem, Prozac may help relieve certain types of pain, but thereaposs a lack of evidence that they help alleviate nerve pain. Additional ongoing clinical trials will help shed light on treating chronic pain with antidepressants. It has been well-documented that tricyclic antidepressants have anti-pain and gut-slowing qualities, and seem to do this by acting on the neurotransmitters serotonin and norepinephrine. However, for long-term preventive care, its best to focus on ergonomics.
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Antidepressants: Definitive Guide - Spine-Health
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Antidepressants: Another weapon against chronic pain
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What Is GABA And How Does It Affect Your Sleep?
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