Cobalt chloride hypoxia

Nov 2 20One of the most commonly used models is cobalt chlorideinduced chemical hypoxia because it stabilizes hypoxia inducible factors and under normoxic conditions. It is also responsible for mitochondrial DNA damage in rat neuronal PCcells. The use of cobalt chloride as a chemical hypoxia model. This model has several advantages, and currently, there is a substantial amount of scattered information about how this model works. Cobalt (II) Chloride hexahydrate (CoCl6H2O, MW23) is a chemical inducer of hypoxia-inducible factor- 8. One of the most commonly used models is cobalt chlorideinduced chemical hypoxia because it stabilizes hypoxia inducible factors and under normoxic conditions.

Cobalt (II) Chloride hexahydrate (CoCl 6H O, MW23) is a chemical inducer of hypoxia-inducible factor- is product is soluble in water (1mgml yielding a clear, red solution. Sep 1 20The Role of Hypoxia Inducible Factor in Cobalt Chloride Induced Cell Death in Mouse Embryonic Fibroblasts A. I prepare 10-ml of stock solution, but only 50-1ul is used at time. We examined in this study whether cobalt chloride induce HIF-in different concentrations.

Induction and Testing of Hypoxia in Cell Culture

To whom correspondence should be addressed at 4Biochemistry Building, Michigan State University, East. Cobalt chloride induces hypoxia condition in cells by upregulating hypoxia-inducible factor-(HIF-erythropoietin and glycolytic enzymes. I am using cobalt chloride for HIFinduction in cancer cell lines.

Cobalt(II) chloride - Hypoxia-inducible factor-(HIF-1) is the main transcriptional factor activated by hypoxia and it plays a key role in reprogramming tumor growth. Cobalt(II) chloride SynonyCobalt dichloride, Cobalt muriate, Cobaltous chloride, Dichlorocobalt CAS Number. Prepare a 25mM stock solution in sterile dd water, (prepare immediately before use). Induction and Testing of Hypoxia in Cell Culture Aug 1 201. This product is soluble in water (1mgml yielding a clear, red solution).

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